The REGENT-1 Study


We are preparing to evaluate an exciting new non-surgical procedure for the treatment of Type 2 Diabetes and are looking for participants with Type 2 Diabetes to be part of the study.


The REGENT-1 Study Safety and Feasibility of
Endoscopic Application of a Novel Therapy for
Duodenal Mucosal Regeneration in the
Treatment of Type II Diabetes
(REGENT-1 Study)

The FlashGM Study

The REGENT-1 study evaluating an investigational endoscopic
(non-surgical) procedure for the treatment of Type 2 Diabetes, called the
Endogenex procedure, is currently enrolling participants.

The Endogenex procedure is designed to promote regeneration of the
cells in the small intestine that help manage blood sugar levels. During an Endogenex procedure, while the participant is asleep, a doctor uses a small flexible camera to introduce a special device through the mouth to the small intestine. The device is used to apply a precise, controlled, electric
current to the lining (mucosa) of the small intestine.
This delivery of energy is designed to trigger the body’s natural process to promote regeneration of healthy cells that help control blood sugar levels.

Become a participant!

Meet Kim Henshaw who is a participant in type 1 diabetes technology research at the DTRG. Watch Kim explain what it means to her to be a participant in this important area of research.

Get involved

Please contact the Research Group Leader to discuss your options.