The PEARLs study

A feasibility study for a Medtronic Next Generation hybrid closed-loop system

In this study, we wanted to compare how easy it was to use the new experimental Medtronic ‘Enhanced- Advanced Hybrid Closed Loop System’ to earlier versions of the company’s automated insulin delivery systems. We had 21 participants complete the study between 2021 and 2023.

Many participants found the new Medtronic system easier to use and more convenient than the previous models. Blood glucose levels were better managed by the new system, and participants spent more time within the recommended blood glucose range while using the new system as compared with earlier systems. Participants also reported that it was easier to go about their daily lives, and they indicated that their fear of hypoglycaemia was decreased. Just as importantly, we found that the number of pump alarms that went off and the number of fingerstick blood glucose tests performed were dramatically reduced. Set changes and sensor changes were also quicker using the new system. These results of this study will help inform the design of future automated insulin delivery systems.

To read the publication, click here

The PEARLs study

A feasibility study for a Medtronic Next Generation hybrid closed-loop system

In this study, we wanted to compare how easy it was to use the new experimental Medtronic ‘Enhanced- Advanced Hybrid Closed Loop System’ to earlier versions of the company’s automated insulin delivery systems. We had 21 participants complete the study between 2021 and 2023.

Many participants found the new Medtronic system easier to use and more convenient than the previous models. Blood glucose levels were better managed by the new system, and participants spent more time within the recommended blood glucose range while using the new system as compared with earlier systems. Participants also reported that it was easier to go about their daily lives, and they indicated that their fear of hypoglycaemia was decreased. Just as importantly, we found that the number of pump alarms that went off and the number of fingerstick blood glucose tests performed were dramatically reduced. Set changes and sensor changes were also quicker using the new system. These results of this study will help inform the design of future automated insulin delivery systems.

To read the publication, click here