The GLAM study
A feasibility study for a new continuous Glucose/Lactate sensor
Automated insulin delivery systems may benefit from real-time measurements of other molecules or analytes in addition to glucose in order to better predict insulin needs. Multi-analyte sensors are sensors that track multiple different molecules, which could include glucose, lactate (lactic acid), or ketones etc. Wearing a multi-analyte sensor could reduce the burden of wearing multiple devices if an individual wants to track more than one molecule.
This study was the first study to test a multianalyte sensor for both glucose and lactate in humans. Lactate was chosen as a second analyte because it is produced during exercise, and the measurement of lactate could be useful for predicting insulin needs during exercise. The study included 16 adults with type 1 diabetes who wore the multianalyte sensor for 4 days, completing a meal test and an exercise test at St Vincent’s hospital on day 1 and day 4.
Overall, the multianalyte sensor was found to be safe and performed well under the strenuous conditions of the meal test and the exercise test. However, the data generated by the sensor was slightly less accurate than the commercial Guardian 3 sensor and the blood glucose and lactate tests. It was concluded that more testing of this glucose/lactate sensor is required to ensure that the data generated is reliable and to investigate how the sensor performs over a longer period of time.
To read the publication, click here
The GLAM study
A feasibility study for a new continuous Glucose/Lactate sensor
Automated insulin delivery systems may benefit from real-time measurements of other molecules or analytes in addition to glucose in order to better predict insulin needs. Multi-analyte sensors are sensors that track multiple different molecules, which could include glucose, lactate (lactic acid), or ketones etc. Wearing a multi-analyte sensor could reduce the burden of wearing multiple devices if an individual wants to track more than one molecule.
This study was the first study to test a multianalyte sensor for both glucose and lactate in humans. Lactate was chosen as a second analyte because it is produced during exercise, and the measurement of lactate could be useful for predicting insulin needs during exercise. The study included 16 adults with type 1 diabetes who wore the multianalyte sensor for 4 days, completing a meal test and an exercise test at St Vincent’s hospital on day 1 and day 4.
Overall, the multianalyte sensor was found to be safe and performed well under the strenuous conditions of the meal test and the exercise test. However, the data generated by the sensor was slightly less accurate than the commercial Guardian 3 sensor and the blood glucose and lactate tests. It was concluded that more testing of this glucose/lactate sensor is required to ensure that the data generated is reliable and to investigate how the sensor performs over a longer period of time.
To read the publication, click here